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KMID : 0383820080650030230
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Tuberculosis and Respiratory Diseases
2008 Volume.65 No. 3 p.230 ~ p.234
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A Case of Extensive Stage Small Cell Lung Cancer Presenting as an Acute Appendicitis with Perforation
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Shin Dong-Won
Park Sung-Woo
Kim Ki-Up
Jang An-Soo
Park Choon-Sik
Lim Chul-Wan
Koh Eun-Seok
Paik Sang-Hyun
Kim Do-Jin
Choi Moon-Han
Park Seung-Sik
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Abstract
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The incidence of appendiceal metastatic cancer is quite low. In particular, in small cell lung cancer, there is a
very low incidence of a metastasis to the appendix. A 75-years old man with right lower quadrant pain, cough
and sputum was transferred to our hospital. Abdominal CT revealed acute appendicitis with a perforation. The
patient underwent surgery. The frozen sections of the tissue obtained during surgery, indicated a malignancy, but
a right hemicolectomy was not performed due to the patient’s poor general condition. The histology findings of
the appendix were identified as a small cell carcinoma. The abdominal CT scan and chest x-ray at admission
day showed a mass in the right lower lobe, and a further evaluation of the lesion was performed including positron
emission tomography and flexible bronchoscopy with a biopsy. The pathology findings of the lung mass were
also small cell lung cancer. The specimens from both sites stained positive for cytokeratin, cluster designation
56, synaptophysin, chromogranin-A and thyroid transcription factor 1. It was concluded that the appendiceal small
cell cancer originated from the lung.
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KEYWORD
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Appendix, Metastasis, Small cell carcinoma
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